Welcome to Wan Lab@UNMC

Machine Learning and Bioinformatics (MLAB) Lab

The Wan Lab in the Department of Genetics, Cell Biology and Anatomy (GCBA) at University of Nebraska Medical Center (UNMC) is focusing on artificial intelligence (AI), machine learning (ML), bioinformatics, and computational biology, especially in single-cell analysis, multi-omics analysis, spatial transcriptomics, cancer research, intelligent healthcare, and precision medicine. To unravel the mechanisms of molecular biological systems in which enormous amounts of heterogeneous data are usually involved, AI/ML and bioinformatics are perfect tools. Besides collaborating with scientists in cancer biology, metabolism, immunology, pathology and developmental biology, our laboratory is mainly to develop AI/ML and/or data science-based methods to tackle essential biomedical problems in genomics, transcriptomics, epigenetics, proteomics, metabolomics, and interactomes as well as medical imaging data and electronic health records (EHR) data.

We are looking for passionate new PhD students, Postdocs, and Master students to join our team (more info) !

News

08-11-2026
Shibiao is invited to give a seminar talk for Department of Biochemistry and Molecular Biology at UNMC on Oct-12-2026.

08-11-2026
Congratulations to Lusheng for passing his PhD Comprehensive Exam!

08-07-2026
Our team is awarded an NIH/NIAAA R21 Grant to develop deep learning models for BNST (the bed nucleus of the stria terminalis) segmentation and investigate the role of the BNST in adolescent alcohol use. Congratulations to the PI Dr. Jieqiong Wang, MPIs Dr. Jennifer Blackford and Shibiao!

08-02-2026
A research article titled “MetaAMI: A Novel Meta-Learning Approach for Predicting In-Hospital Mortality in Acute Myocardial Infarction” is online at bioRxiv. Congratulations to Bulidierxin!

07-30-2026
A research article titled “WIMOAD: Weighted Integration of Multi-Omics Data with Meta Learning for Alzheimer’s Disease Diagnosis” is accepted by the journal Journal of Alzheimer's Disease. Congratulations to Hanyu!

07-24-2026
Shibiao is invited to give a seminar talk for Department of Pathology, Microbiology, and Immunology at UNMC on Sep-09-2026.

... see all News