Welcome to Wan Lab@UNMC

Machine Learning and Bioinformatics (MLAB) Lab

The Wan Lab in the Department of Genetics, Cell Biology and Anatomy (GCBA) at University of Nebraska Medical Center (UNMC) is focusing on artificial intelligence (AI), machine learning (ML), bioinformatics, and computational biology, especially in single-cell analysis, multi-omics analysis, spatial transcriptomics, cancer research, intelligent healthcare, and precision medicine. To unravel the mechanisms of molecular biological systems in which enormous amounts of heterogeneous data are usually involved, AI/ML and bioinformatics are perfect tools. Besides collaborating with scientists in cancer biology, metabolism, immunology, pathology and developmental biology, our laboratory is mainly to develop AI/ML and/or data science-based methods to tackle essential biomedical problems in genomics, transcriptomics, epigenetics, proteomics, metabolomics, and interactomes as well as medical imaging data and electronic health records (EHR) data.

We are looking for passionate new PhD students, Postdocs, and Master students to join our team (more info) !

News

09-22-2026
A review article titled “A Comprehensive Review on RNA Subcellular Localization Prediction” is accepted by the journal Briefings in Functional Genomics. Congratulations to Cece, Xuehuan and Nick!

09-22-2026
Shibiao gives an invited seminar talk for Breast Cancer Translational Working Group at UNMC entitled "Leveraging AI to Advanced Health Equity for Breast Cancer".

09-22-2026
A research article titled “MetaPaCS: A Novel Meta-Learning Framework for Pancreatic Cancer Subtype Identification” is accepted by the journal Advanced Intelligent Systems. Congratulations to Nick, Mengtao and Xinchao!

09-18-2026
Shibiao gives an invited talk for National Cancer Institute (NCI) Childhood Cancer Data Initiative (CCDI) Symposium entitled "Leveraging AI to Characterize Acute Leukemia" at Rockville, MD.

09-16-2026
Shibiao is invited to attend the inaugural UNL-UNMC Summit to be held on Sep-30.

09-16-2026
Shibiao is featured and highlighted in the top news of UNMC Today for the recently funded NSF FEC Grant. Congratulations to the whole lab!

... see all News